| Date | Location | Result | |
| 03-03-06 | Roberts Stadium, Evansville, Ind. | Drury 67, Kentucky Wesleyan 66 | Box score |
| 02-25-06 | Richard F. Scharf Alumni Fieldhouse | Kentucky Wesleyan 74, Saint Joseph's 64 | Box score |
| 02-23-06 | Nicoson Hall, Indianapolis, Ind. | Kentucky Wesleyan 59, Indianapolis 57 | Box score |
| 02-18-06 | Owensboro Sportscenter, Owensboro, Ky. | Northern Kentucky 62, Kentucky Wesleyan 60 | Box score |
| 02-16-06 | Owensboro Sportscenter, Owensboro, Ky. | Bellarmine 73, Kentucky Wesleyan 68 | Box score |
| 02-11-06 | Neil Carey Arena, Romeoville, Ill. | Lewis 62, Kentucky Wesleyan 59 | Box score |
| 02-09-06 | DeSimone Gymnasium, Somers, Wis. | Kentucky Wesleyan 66, Wisconsin-Parkside 53 | Box score |
| 02-04-06 | Owensboro Sportscenter, Owensboro, Ky. | Kentucky Wesleyan 85, Southern Indiana 75 | Box score |
| 02-02-06 | Owensboro Sportscenter, Owensboro, Ky. | Kentucky Wesleyan 73, Oakland City 51 | Box score |
| 01-28-06 | Owensboro Sportscenter, Owensboro, Ky. | Kentucky Wesleyan 63, Indianapolis 59 | Box score |
| 01-26-06 | Owensboro Sportscenter, Owensboro, Ky. | Kentucky Wesleyan 70, Saint Joseph's 62 | Box score |
| 01-21-06 | Weiser Gymnasium, Springfield, Mo. | Drury 79, Kentucky Wesleyan 71 | Box score |
| 01-19-06 | Mason-Hapin Fieldhouse, Kansas City, Mo. | Kentucky Wesleyan 68, Rockhurst 60 | Box score |
| 01-14-06 | Owensboro Sportscenter, Owensboro, Ky. | Quincy 67, Kentucky Wesleyan 64 | Box score |
| 01-12-06 | Owensboro Sportscenter | Kentucky Wesleyan 77, SIU-Edwardsville 72 | Box score |
| 01-07-06 | Knights Hall, Louisville, Ky. | Bellarmine 78, Kentucky Wesleyan 71 | Box score |
| 01-05-06 | Regents Hall, Highland Heights, Ky. | Northern Kentucky 62, Kentucky Wesleyan 47 | Box score |
| 12-30-05 | Matthaei Gymnasium, Detroit, Mich. | Kentucky Wesleyan 76, Wayne State 72 | Box score |
| 12-28-05 | O'Neill Arena, University City, Mich. | Saginaw Valley 74, Kentucky Wesleyan 61 | Box score |
| 12-19-05 | Health & Sports Ctr., Miami Shores, Fla. | Kentucky Wesleyan 73, Barry 59 | Box score |
| 12-18-05 | George Mayer Gym, Fort Lauderdale, Fla. | Nova Southeastern 75, Kentucky Wesleyan 58 | Box score |
| 12-10-05 | Owensboro Sportcenter, Owensboro, Ky. | Kentucky Wesleyan 80, Wisconsin-Parkside 58 | Box score |
| 12-08-05 | Owensboro Sportscenter, Owensboro, Ky. | Kentucky Wesleyan 83, Lewis 68 | Box score |
| 12-03-05 | Bullman Multi-Purpose Bldg. Rolla, Mo. | Missouri-Rolla 64, Kentucky Wesleyan 55 | Box score |
| 12-01-05 | Mark Twain Building, St. Louis, Mo. | Missouri-St. Louis 64, Kentucky Wesleyan 56 | Box score |
| 11-26-05 | Owensboro Sportscenter, Owensboro, Ky. | Kentucky Wesleyan 93, Brescia 63 | Box score |
| 11-22-05 | Martin, Tenn. Skyhawk Arena | Tennessee-Martin 75, Kentucky Wesleyan 63 | Box score |
| 11-17-05 | Johnson Center, Oakland City, Ind. | Kentucky Wesleyan 71, Oakland City 59 | Box score |